Mette Hønningen was born in Copenhagen, Denmark, in 1944. She entered the Ballet School of the Royal Theatre in 1956. She joined the Royal Danish Ballet, was promoted to soloist in 1967 and to principal in 1976. She developed her strong technique under Vera Volkova and covered a broad repertory. Made her debut in 1964 as the pupil in Flindt's The Lesson with Henning Kronstam. She also got known for the title role in the Disney film Ballerina in 1966.
Aili in Moon Reindeer and Carmen (1965), La Sylphide (1976), Tetley's Pierrot Lunaire (1968), Greening (1978), Voluntaires (1978) and Firebird (1981), Alvin Ailey's Memoria (1981), Caverna Magica (1986 and Witness (created specially for her in 1986), Sugarplum Fairy in Nutcracker (1971), Lady Capulet in Romeo and Juliet (1974), Odette/Odile in Swan Lake (1975), Hippolyta/Titania in A Midsummer Nights Dream (1980), Balanchine's Symphony in C (1973), Four Temperaments (1977) and Serenade (1978), and Ballerina in Lander's Etudes.