Olga Moiseyeva was born in Leningrad in 1928. She graduated from the Vaganova School (class of Agrippina Vaganova) in 1948. She was well suited for the grand heroic classical roles. She created Mekhmene Banu in The Legend of Love (Grigorovich), Getrude in Hamlet (K. Sergeyev) and Bianca in Othello (Chabukiani). Other important roles include Zarema in The Fountain of Bakhchisarai (Zakharov), title role in Laurencia (Chabukiani), Aegina in Spartacus (Jakobson), Siumbike in Shurale (Jakobson), Nikiya in La Bayadère, title role in Giselle, Kitri in Don Quixote and Odette-Odile in Swan Lake.
She retired from the stage in 1973 and has been a leading repetiteur at the Kirov guiding the careers of Galina Mezentseva and Altynai Asylmuratova. She was teacher of Yulia Makhalina and Svetlana Zakharova in their years as young soloists.