Anna Nikukina was born in Moscow. After graduation from the Moscow Academic Choreography School (class of Elena Vatulya) she was admitted to the ballet company of the Bolshoi Theatre in 2002. She rehearses with Ekaterina Maximova. In 2004, at the age of 19 years, she danced for the first time Odette-Odile in Swan Lake.
Marie in The Nutcracker, Liuska in The Golden Age, River Kongo in Pharao's Daughter, Shadow (2nd and 3rd variation) in La Bayadere, and roles in La Sylphide, Passacaglia, Giselle, Sleeping Beauty, Legend of Love, Swan Lake and Raymonda amoong others.